2024年3月19日发(作者：步飞宇)

专利内容由知识产权出版社提供

专利名称：Semi-synthetic glycosaminoglycans

containing alpha-L-galacturonic acid

substituted with nucleophilic radicals in

position 3

发明人：Piani, Silvano,Marchi, Egidio,Tamagnone,

Gianfranco,Ungarelli, Fabrizio

申请号：EP93103847.5

申请日：19930310

公开号：EP0565862A2

公开日：19931020

摘要：The synthesis of new semi-synthetic glycosaminoglycans is described in which

one of the saccharide units characteristic of glycosaminoglycans with heparin or heparan

structure, more specifically that of α-L-iduronic-2-O-sulfate acid, has undergone a

structural modification, entirely or in part, with transformation into α-L-galacturonic acid

substituted with nucleophilic radicals in position 3. These new semi-synthetic

glycosaminoglycans of general formula IV have good pharmaceutical properties in that

they may also be absorbed orally and have good anti-thrombotic activity accompanied by

low risk of hemorrhage and reduced anti-coagulating activity.

申请人：ALFA WASSERMANN S.p.A.

地址：Contrada Sant'Emidio I-65020 Alanno Scalo (Pescara) IT

国籍：IT

代理机构：Kraus, Walter, Dr.

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2024年3月19日发(作者：步飞宇)

专利内容由知识产权出版社提供

专利名称：Semi-synthetic glycosaminoglycans

containing alpha-L-galacturonic acid

substituted with nucleophilic radicals in

position 3

发明人：Piani, Silvano,Marchi, Egidio,Tamagnone,

Gianfranco,Ungarelli, Fabrizio

申请号：EP93103847.5

申请日：19930310

公开号：EP0565862A2

公开日：19931020

摘要：The synthesis of new semi-synthetic glycosaminoglycans is described in which

one of the saccharide units characteristic of glycosaminoglycans with heparin or heparan

structure, more specifically that of α-L-iduronic-2-O-sulfate acid, has undergone a

structural modification, entirely or in part, with transformation into α-L-galacturonic acid

substituted with nucleophilic radicals in position 3. These new semi-synthetic

glycosaminoglycans of general formula IV have good pharmaceutical properties in that

they may also be absorbed orally and have good anti-thrombotic activity accompanied by

low risk of hemorrhage and reduced anti-coagulating activity.

申请人：ALFA WASSERMANN S.p.A.

地址：Contrada Sant'Emidio I-65020 Alanno Scalo (Pescara) IT

国籍：IT

代理机构：Kraus, Walter, Dr.

更多信息请下载全文后查看