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早产儿脑白质损伤早期MRI-DWI的分类、演变及临床意义
2024年5月12日发(作者：买冬莲)
早产儿脑白质损伤早期MRI-DWI的分类、演变及临床意义
段洋;毛健;富建华;李娟;薛辛东;王晓明;陈丽英
【期刊名称】《山东医药》
【年(卷),期】2011(51)28
【摘 要】目的 结合常规MRI和弥散加权成像(DWI)探讨早产儿脑白质损伤
(CWMD)的较客观分类方法,动态评价不同类型CWMD的变化规律及临床意义.方
法 517例早产儿行常规MRI和DWI检查,确诊早产儿CWMD212例,对其中55
例随访.结果随病变累及区域数目不同,异常信号有特征性分布及形态学改变,呈现一
系列动态变化,并与神经发育结局有较好的相关性.根据早期CWMD类型可以预测
后期发生脑室周围白质软化(PVL)的类型,反之根据PVL类型可以推测早期CWMD
类型.早期(1周内)DWI能提早发现病变,在一定程度上预示预后.常规MRI晚期(3
周左右)检查能高度预测患儿预后.结论常规MRI和DWI相结合可动态观察
CWMD病变受累区域,与形态学相结合可较客观评价患者预后,并对高危早产儿进
行早期合理康复.%Objective To explore the classification, evoluation and
clinical significance of premature infants with cerebral white matter
damage (CWMD) diagnosed by MRI-DWI. Methods Conventional MRI and
DW1 were performed on 517 premature infants, 212 cases were diagnosed
as CWMD. Follow-up was performed on 55 cases of the 212 ones. Results
Abnormal signal in MRI had its distinctive distribution and morphology.
The abnormal signal presented a serial evolution. Considerable consistency
occurred between the type of lesion and neurological development
outcome. The type of CWMD in the earlier period could predict the type of
periventricular leukomalacia (PVL) in the later period, the type of PVL could
predict the type of CWMD too. In the earlier period (in the first week) ,
DWI could detect pathology ahead of MRI and indicate prognosis in a
degree. While in the later period (about the 3th week), MRI could predict
exact neurological development outcome. Conclusion MRI-DWI can be
used to observe the dynamic lesion regions of CWMD, which combined
with pathology can assess prognosis and perform reasonable rehabilitation
on premature infants with CWMD.
【总页数】5页(P38-40,后插1,封3)
【作 者】段洋;毛健;富建华;李娟;薛辛东;王晓明;陈丽英
【作者单位】天津医科大学第二医院,天津300211;中国医科大学附属盛京医院;中
国医科大学附属盛京医院;中国医科大学附属盛京医院;中国医科大学附属盛京医院;
中国医科大学附属盛京医院;中国医科大学附属盛京医院
【正文语种】中 文
【中图分类】R722.6
【相关文献】
1.磁共振弥散加权成像对早产儿脑白质损伤的早期评价和诊断价值 [J], 安娜;李昉;
苏丹丹;张欢欢;李晨
-6、NES以及新生儿颅脑超声对早期诊断早产儿脑白质损伤的应用价值 [J],
张娴;赵琳;李艳红;张俊涛;赵梦茹
3.探讨头颅MRI-DWI联合血清NSE检测在诊断早产儿局灶性脑白质损伤中的应
用价值 [J], 张林;赵朋娜;张倩;张高峰;杨晓云
-6、NES以及新生儿颅脑超声对早期诊断早产儿脑白质损伤的应用价值 [J],
张娴;赵琳;李艳红;张俊涛;赵梦茹
5.振幅整合脑电图监测在早产儿脑白质损伤早期诊断及预后评估中的应用价值 [J],
杨丽;薛梅;朱诗瑞;樊晓艳
因版权原因，仅展示原文概要，查看原文内容请购买
2024年5月12日发(作者：买冬莲)
早产儿脑白质损伤早期MRI-DWI的分类、演变及临床意义
段洋;毛健;富建华;李娟;薛辛东;王晓明;陈丽英
【期刊名称】《山东医药》
【年(卷),期】2011(51)28
【摘 要】目的 结合常规MRI和弥散加权成像(DWI)探讨早产儿脑白质损伤
(CWMD)的较客观分类方法,动态评价不同类型CWMD的变化规律及临床意义.方
法 517例早产儿行常规MRI和DWI检查,确诊早产儿CWMD212例,对其中55
例随访.结果随病变累及区域数目不同,异常信号有特征性分布及形态学改变,呈现一
系列动态变化,并与神经发育结局有较好的相关性.根据早期CWMD类型可以预测
后期发生脑室周围白质软化(PVL)的类型,反之根据PVL类型可以推测早期CWMD
类型.早期(1周内)DWI能提早发现病变,在一定程度上预示预后.常规MRI晚期(3
周左右)检查能高度预测患儿预后.结论常规MRI和DWI相结合可动态观察
CWMD病变受累区域,与形态学相结合可较客观评价患者预后,并对高危早产儿进
行早期合理康复.%Objective To explore the classification, evoluation and
clinical significance of premature infants with cerebral white matter
damage (CWMD) diagnosed by MRI-DWI. Methods Conventional MRI and
DW1 were performed on 517 premature infants, 212 cases were diagnosed
as CWMD. Follow-up was performed on 55 cases of the 212 ones. Results
Abnormal signal in MRI had its distinctive distribution and morphology.
The abnormal signal presented a serial evolution. Considerable consistency
occurred between the type of lesion and neurological development
outcome. The type of CWMD in the earlier period could predict the type of
periventricular leukomalacia (PVL) in the later period, the type of PVL could
predict the type of CWMD too. In the earlier period (in the first week) ,
DWI could detect pathology ahead of MRI and indicate prognosis in a
degree. While in the later period (about the 3th week), MRI could predict
exact neurological development outcome. Conclusion MRI-DWI can be
used to observe the dynamic lesion regions of CWMD, which combined
with pathology can assess prognosis and perform reasonable rehabilitation
on premature infants with CWMD.
【总页数】5页(P38-40,后插1,封3)
【作 者】段洋;毛健;富建华;李娟;薛辛东;王晓明;陈丽英
【作者单位】天津医科大学第二医院,天津300211;中国医科大学附属盛京医院;中
国医科大学附属盛京医院;中国医科大学附属盛京医院;中国医科大学附属盛京医院;
中国医科大学附属盛京医院;中国医科大学附属盛京医院
【正文语种】中 文
【中图分类】R722.6
【相关文献】
1.磁共振弥散加权成像对早产儿脑白质损伤的早期评价和诊断价值 [J], 安娜;李昉;
苏丹丹;张欢欢;李晨
-6、NES以及新生儿颅脑超声对早期诊断早产儿脑白质损伤的应用价值 [J],
张娴;赵琳;李艳红;张俊涛;赵梦茹
3.探讨头颅MRI-DWI联合血清NSE检测在诊断早产儿局灶性脑白质损伤中的应
用价值 [J], 张林;赵朋娜;张倩;张高峰;杨晓云
-6、NES以及新生儿颅脑超声对早期诊断早产儿脑白质损伤的应用价值 [J],
张娴;赵琳;李艳红;张俊涛;赵梦茹
5.振幅整合脑电图监测在早产儿脑白质损伤早期诊断及预后评估中的应用价值 [J],
杨丽;薛梅;朱诗瑞;樊晓艳
因版权原因，仅展示原文概要，查看原文内容请购买